SRP5316

RIPK3, active, GST tagged human

PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 別名: RIP3
• CAS番号: 236750-39-3
• UNSPSCコード: 51111800
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in baculovirus infected Sf9 cells
• 製品種目: PRECISIO^®
• アッセイ: ≥70% (SDS-PAGE)
• フォーム: buffered aqueous glycerol solution
• 比活性: 30-51 nmol/min·mg
• 分子量: ~96 kDa
• NCBIアクセッション番号: NM_006871
• アプリケーション: cell analysis
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... RIPK3(11035)

詳細

詳細

Receptor interacting serine/threonine kinase 3 (RIPK3)/RIP3 is a serine/threonine kinase. It belongs to the receptor-interacting protein family. RIPK3 is characterized with a conserved amino-terminal kinase domain, which is necessary for necrosis. The gene RIPK3 is mapped to human chromosome 14. The encoded protein is composed of 518 amino acids.

生物化学的／生理学的作用

Receptor interacting serine/threonine kinase 3 (RIPK3) activates necroptotic cell death and has a role in inflammatory signaling. The protein also functions in controlling viral infections, platelet functions, hemostasis and thrombosis. RIPK3 is highly expressed during cutaneous wound repair and also stimulates interleukin-1 β production.

物理的形状

50 mM Tris-HCl溶液（pH 7.5、150 mM NaCl、10 mM グルタチオン、0.1 mM EDTA、0.25 mM DTT、0.1 mM PMSF、25％ グリセロール）

調製ノート

開封後は少量ずつに分注して－70℃で保管してください。操作を反復したり凍結融解を何度も繰り返したりしないでください。

法的情報

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable