SML3503

EN523

≥98% (HPLC)

• 別名: 1-(5-Methyl-2-furanyl)-4-(1-oxo-2-propen-1-yl)-2-piperazinone
• 実験式（ヒル表記法）: C₁₂H₁₄N₂O₃
• CAS番号: 2094893-05-5
• 分子量: 234.25
• MDL番号: MFCD32859220
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: O=C1N(CCN(C1)C(C=C)=O)C2=CC=C(O2)C
• InChI: 1S/C12H14N2O3/c1-3-10(15)13-6-7-14(11(16)8-13)12-5-4-9(2)17-12/h3-5H,1,6-8H2,2H3
• InChI Key: KYXPDOMFYBFXKO-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1

EN523 is a cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1. EN523 does not inhibit OTUB1 deubiquitination activity and serves as OTUB1 recruiter.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable