SML2114

ZD7155 hydrochloride

≥97% (HPLC)

• 別名: 5,7-Diethyl-3,4-dihydro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one hydrochloride, ZD 7155
• 実験式（ヒル表記法）: C₂₆H₂₆N₆O · HCl
• CAS番号: 146709-78-6
• 分子量: 474.99
• MDL番号: MFCD00921888
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥97% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 2 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: CCC1=C(C2=CC(CC)=N1)CCC(N2CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5)=O.Cl
• InChI: 1S/C26H26N6O.ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H
• InChI Key: NAGGAAHTUXEGFG-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Selective Angiotensin II AT1 antagonist

ZD7155 is a potent selective Angiotensin II AT1 antagonist. In one study ZD 7155 was found to be longer-acting and approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3