SML1809

PPTN trifluoroacetate salt

≥98% (HPLC)

• 別名: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid trifluoroacetate salt
• 実験式（ヒル表記法）: C₂₉H₂₄F₃NO₂ · C₂HF₃O₂
• CAS番号: 1160271-30-6
• 分子量: 589.52
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: 10 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: OC(C1=CC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2C(C4=CC=C(C5CCNCC5)C=C4)=C1)=O.FC(F)(C(O)=O)F

詳細

生物化学的／生理学的作用

PPTN is a very potent (IC₅₀ = 1 nM) P2Y14 receptor antagonist that does not interact with any other P2Y receptor at concentrations up to 10 μM. PPTN blocks UDP-glucose inhibition of forskolin-induced cAMP accumulation, and neutrophil chemotaxis towards UDP-glucose gradients with nM potency.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable