SML1720

ATI-2341 trifluoroacetate salt

≥95% (HPLC)

• 別名: ATI 2341 trifluoroacetate salt, N-(1-Ohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl- L-leucine, Pal-MGYQKKLRSMTDKYRL, Pal-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu
• 実験式（ヒル表記法）: C₁₀₄H₁₇₈N₂₆O₂₅S₂ · xC₂HF₃O₂
• CAS番号: 1337878-62-2
• 分子量: 2256.82 (free base basis)
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: film
• 色: colorless
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

生物化学的／生理学的作用

ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341 promotes the mobilization of PMNs and HSPCs in the peripheral circulation of both mice and monkeys.

ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4).

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable