SML1623

MSP-3

≥98% (HPLC)

• 別名: N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
• 実験式（ヒル表記法）: C₁₆H₁₉NO₃S
• CAS番号: 1820968-63-5
• 分子量: 305.39
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825508
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: oil
• 色: white to beige
• 保管温度: room temp
• SMILES記法: O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
• InChI: 1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
• InChI Key: HCUVEUVIUAJXRB-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

TRPV1 agonist protective against oxidative stress

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable