SML1616

ICA-069673

≥98% (HPLC)

• 別名: ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide
• 実験式（ヒル表記法）: C₁₁H₆ClF₂N₃O
• CAS番号: 582323-16-8
• 分子量: 269.63
• MDL番号: MFCD20926351
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825502
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: room temp
• SMILES記法: O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2
• InChI: 1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
• InChI Key: IIBSHMFXVWTQSJ-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.

ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3