SML1521

Irsogladine maleate

≥98% (HPLC)

• 別名: 2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazine maleate, 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine (2Z)-2-butenedioate (1:1), Gaslon N, MN 1695
• 実験式（ヒル表記法）: C₉H₇Cl₂N₅ ·C₄H₄O₄
• CAS番号: 84504-69-8
• 分子量: 372.16
• MDL番号: MFCD00865153
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825938
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 15 mg/mL, clear
• 保管温度: room temp
• SMILES記法: C[C@]1([H])[C@@](C)(O)CC2=C(C(OC)=C(OC)C(OC)=C2)C3=C(OC)C4=C(OCO4)C=C3C1
• InChI: 1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3/t12-,23-/m0/s1
• InChI Key: ZWRRJEICIPUPHZ-MYODQAERSA-N

詳細

生物化学的／生理学的作用

Irsogladine maleate is an inhibitor of phosphodiesterase 4 (PDE4) with gastroprotective activity.

Irsogladine maleate is an inhibitor of phosphodiesterase 4 (PDE4) with gastroprotective activity. Irsogladine maleate is a mucosal protective drug with a number of activites including facilitation of gap junctional intercellular communication, inhibition of the reduced gastric mucosal blood flow response, and suppression of reactive oxygen species (ROS) production.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable