SML1405

MS37452

≥98% (HPLC)

• 別名: 1-(2,3-Dimethoxybenzoyl)-4-[(3-methylphenoxy)acetyl]-piperazine (9CI), 1-[4-(2,3-Dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanonemethylphenoxy)acetyl]-piperazine (9CI)
• 実験式（ヒル表記法）: C₂₂H₂₆N₂O₅
• CAS番号: 423748-02-1
• 分子量: 398.45
• MDL番号: MFCD03134667
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825852
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 輸送温度: wet ice
• 保管温度: −20°C
• SMILES記法: O=C(COC1=CC(C)=CC=C1)N2CCN(C(C3=CC=CC(OC)=C3OC)=O)CC2
• InChI: 1S/C22H26N2O5/c1-16-6-4-7-17(14-16)29-15-20(25)23-10-12-24(13-11-23)22(26)18-8-5-9-19(27-2)21(18)28-3/h4-9,14H,10-13,15H2,1-3H3
• InChI Key: LUMCNRKHZRYQOV-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. MS37452 inhibits CBX7 binding to INK4/ARF gene locus, and induces decline of p14/ARF and p16/INK4a in human PC3 cells.

MS37452 is a selective Chromobox homolog 7 (CBX7) modulator.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable