SML0804

(S)-CPP sodium salt

≥96% (HPLC)

• 別名: (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
• 実験式（ヒル表記法）: C₉H₈ClO₂ · Na
• CAS番号: 194979-70-9
• 分子量: 206.60
• MDL番号: MFCD28118980
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825602
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥96% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: H₂O: 20 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
• InChI: 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
• InChI Key: HMHPCHNNVOLTFC-QRPNPIFTSA-M

詳細

生物化学的／生理学的作用

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable