SML0446

A-419259 trihydrochloride

≥98% (HPLC)

• 別名: 7-[Trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride, A419259 trihydrochloride
• 実験式（ヒル表記法）: C₂₉H₃₄N₆O · 3HCl
• CAS番号: 364042-47-7
• 分子量: 592.00
• MDL番号: MFCD19690922
• UNSPSCコード: 12352200
• PubChem Substance ID: 329824728
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 10 mg/mL (clear solution)
• 保管温度: room temp
• SMILES記法: Cl.Cl.Cl.CN1CCN(CC1)[C@H]2CC[C@@H](CC2)n3cc(-c4ccc(Oc5ccccc5)cc4)c6c(N)ncnc36
• InChI: 1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;
• InChI Key: ALRMEQIQFCUAMR-KOONDFAVSA-N

詳細

生物化学的／生理学的作用

A-419259 is a potent inhibitor of Src family kinases.

A-419259 is a potent inhibitor of Src family kinases. IC₅₀ values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM.

特徴および利点

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安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable