SML0367

VK3-OCH3

≥98% (HPLC)

• 別名: 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-naphthoquinone
• 実験式（ヒル表記法）: C₁₄H₁₄O₃S
• CAS番号: 255906-59-3
• 分子量: 262.32
• MDL番号: MFCD22575003
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825368
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: light orange to dark orange
• 溶解性: DMSO: 10 mg/mL (clear solution)
• 保管温度: 2-8°C
• SMILES記法: COCCSC1=C(C)C(=O)c2ccccc2C1=O
• InChI: 1S/C14H14O3S/c1-9-12(15)10-5-3-4-6-11(10)13(16)14(9)18-8-7-17-2/h3-6H,7-8H2,1-2H3
• InChI Key: JTCRCMIBIBLUOK-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

VK3-OCH3 is an analog of Vitamin K3 (Menadione) with potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.

安全性情報

• ピクトグラム: GHS09
• シグナルワード: Warning
• 危険有害性情報: H400
• 注意書き: P273 - P391 - P501
• 危険有害性の分類: Aquatic Acute 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable