M9429

メナジオン

meets USP testing specifications

• 別名: 2-メチル-1,4-ナフトキノン, ビタミンK₃
• 実験式（ヒル表記法）: C₁₁H₈O₂
• CAS番号: 58-27-5
• 分子量: 172.18
• Beilstein: 1908453
• EC Number: 200-372-6
• MDL番号: MFCD00001681
• UNSPSCコード: 12352205
• PubChem Substance ID: 24897335
• NACRES: NA.21

特性

• 由来生物: synthetic (organic)
• 品質水準: 200
• 認証: USP/NF; meets USP testing specifications
• アッセイ: 98.5-101.0% dry basis
• 形状: solid
• mp: 105-107 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• SMILES記法: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI Key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• 遺伝子情報: human ... NQO1(1728)

詳細

詳細

Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.

アプリケーション

Menadione has been used:

• to treat HL-60 cells as positive control for apoptosis for flow cytometry
• as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization
• to treat HaCaT cell line, for quantifying total and oxidised glutathione

生物化学的／生理学的作用

Menadione is an oxidative stress inducer.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H317,H319,H335,H410
• 注意書き: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves