SML0284

Mycophenolate mofetil

≥98% (HPLC)

• 別名: (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester, RS 61443, TM-MMF
• 実験式（ヒル表記法）: C₂₃H₃₁NO₇
• CAS番号: 128794-94-5
• 分子量: 433.49
• MDL番号: MFCD00867568
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825292
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: ≥15 mg/mL
• 保管温度: room temp
• SMILES記法: COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN3CCOCC3
• InChI: 1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+
• InChI Key: RTGDFNSFWBGLEC-SYZQJQIISA-N
• 遺伝子情報: human ... IMPDH1(3614) , IMPDH2(3615)

詳細

アプリケーション

Mycophenolate mofetil has been used to treat wild-type embryos for inhibiting nucleotide synthesis.

生物化学的／生理学的作用

Mycophenolate mofetil functions as a rate-limiting enzyme in de novo synthesis of guanosine nucleotides.

Mycophenolate mofetil is a prodrug of mycophenolic acid (Cat. # M5255) that is cleaved by nonspecific esterases in vivo to produce the parent compound. Mycophenolic acid blocks inosine monophosphate dehydrogenase and is a potent immunosuppresive agent.

安全性情報

• ピクトグラム: GHS07,GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302 - H360D - H372 - H410
• 注意書き: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable