SML0241

Ganirelix acetate salt

≥95% (HPLC), lyophilized powder, GnRH antagonist

• 別名: Antagon, N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino)methylene]-D-lysyl-L-leucyl-N6-[bis(ethylamino)methylene]-L-lysyl-L-prolyl-D-alaninamide diacetate, Orgalutran
• 実験式（ヒル表記法）: C₈₀H₁₁₃ClN₁₈O₁₃ · 2C₂H₄O₂
• CAS番号: 129311-55-3
• 分子量: 1690.42
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 製品名: Ganirelix acetate salt, ≥95% (HPLC)
• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: lyophilized powder
• 色: white
• 保管温度: −20°C
• SMILES記法: Clc1ccc(cc1)C[C@H](NC(=O)C(NC(=O)C)Cc5cc6c(cc5)cccc6)C(=O)N[C@@H](Cc4cnccc4)C(=O)N[C@H](CO)C(=O)N[C@H](Cc3ccc(cc3)O)C(=O)N[C@H](CCCCN=C(NCC)NCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN=C(NCC)NCC)C(=O)N2C(CCC2)C(=O)N[C@H](C)C(=O)N.OC(=O)C.OC(=O)C
• InChI: 1S/C80H113ClN18O13.2C2H4O2/c1-9-84-79(85-10-2)88-38-17-15-24-60(70(104)94-62(41-49(5)6)71(105)93-61(25-16-18-39-89-80(86-11-3)87-12-4)78(112)99-40-20-26-68(99)77(111)90-50(7)69(82)103)92-73(107)64(44-53-30-35-59(102)36-31-53)97-76(110)67(48-100)98-75(109)66(46-55-21-19-37-83-47-55)96-74(108)65(43-52-28-33-58(81)34-29-52)95-72(106)63(91-51(8)101)45-54-27-32-56-22-13-14-23-57(56)42-54;2*1-2(3)4/h13-14,19,21-23,27-37,42,47,49-50,60-68,100,102H,9-12,15-18,20,24-26,38-41,43-46,48H2,1-8H3,(H2,82,103)(H,90,111)(H,91,101)(H,92,107)(H,93,105)(H,94,104)(H,95,106)(H,96,108)(H,97,110)(H,98,109)(H2,84,85,88)(H2,86,87,89);2*1H3,(H,3,4)/t50-,60-,61+,62+,63?,64-,65+,66+,67-,68?;;/m1../s1
• InChI Key: OVBICQMTCPFEBS-HYVLHXRFSA-N

詳細

生物化学的／生理学的作用

Ganirelix is a decapeptide GnRH antagonist.

Ganirelix is a decapeptide GnRH antagonist. Ganirelix acts by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable