SMB01019

Amorfrutin A

≥90% (LC/MS-ELSD)

• 別名: 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylethyl)benzoic acid, 3-hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid
• 実験式（ヒル表記法）: C₂₁H₂₄O₄
• CAS番号: 80489-90-3
• 分子量: 340.41
• MDL番号: MFCD23703108
• UNSPSCコード: 12352205
• NACRES: NA.25

特性

• 由来生物: plant
• アッセイ: ≥90% (LC/MS-ELSD)
• フォーム: solid
• 分子量: 340.41
• 溶解性: water: slightly soluble
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: −20°C
• SMILES記法: O(C)c1c(c(c(c(c1)CCc2ccccc2)C(=O)O)O)CC=C(C)C
• InChI: 1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)
• InChI Key: CTNFTPUIYFUXBE-UHFFFAOYSA-N

詳細

詳細

Amorfrutin A is a stilbenoid compound commonly present in plants like Glycyrrhiza foetida, Glycyrrhiza acanthocarpa, Cajanus cajan, and Amorpha fruticosa. Current research indicates that this naturally occurring metabolite possesses diverse biological activities, including anti-inflammatory, anticancer, antidiabetic, and antimicrobial properties.

アプリケーション

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生物化学的／生理学的作用

According to the existing research, Amorfrutin-A demonstrated its ability to inhibit NF-κB activity, a pivotal regulator of genes governing a wide range of cellular functions, such as immune responses, apoptosis, tumor growth, and tissue development. Furthermore, it exhibits anti-inflammatory properties in colon cells by interacting with the nuclear receptor PPARγ, resulting in the reduced expression and secretion of inflammatory mediators. This suggests its potential for treating conditions like inflammatory bowel diseases. Additionally, it also exhibited antidiabetic activity through binding to and activating the nuclear receptor PPARγ.

特徴および利点

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

その他情報

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安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable