SMB00515

Afzelin

≥90% (LC/MS-UV)

• 別名: 3,4′,5,7-Tetrahydroxyflavone 3-rhamnoside, Afzeloside, Kaempferin, Kaempferol 3-O-alpha-L-rhamnoside, Kaempferol 3-rhamnoside
• 実験式（ヒル表記法）: C₂₁H₂₀O₁₀
• CAS番号: 482-39-3
• 分子量: 432.38
• MDL番号: MFCD00210589
• UNSPSCコード: 12352205
• PubChem Substance ID: 329825042
• NACRES: NA.25

特性

• アッセイ: ≥90% (LC/MS-UV)
• 形状: solid
• 溶解性: DMSO: 1 mg/mL
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: −20°C
• SMILES記法: OC1=CC(O)=C(C(C(O[C@H]2[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)=C(C3=CC=C(O)C=C3)O4)=O)C4=C1
• InChI: 1S/C21H20O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-18,21-25,27-28H,1H3/t8-,15-,17+,18+,21-/m0/s1
• InChI Key: SOSLMHZOJATCCP-AEIZVZFYSA-N

詳細

詳細

Afzelin is a natural product derived from a plant source. Ficus palmata and Nymphaea odoratam are the major sources of afzelin, a flavonol glycoside.

アプリケーション

DNA-protective, antioxidant, anti-inflammatory, UV-absorbing and anti-bacterial activities. Afzelin has been used in HPLC (high performance liquid chromomatography) analysis of Comarum palustre L. extract to detect its major compounds.

DNA-protective, antioxidant, and anti-inflammatory, UV-absorbing activity, anti-bacterial activities.

生物化学的／生理学的作用

NOS inhibitor, NADPH oxidase inhibitor, Afzelin is known to possess antibacterial, anti-inflammatory, anti-apoptotic and anti-tumor activities. Afzelin might serve as an effective treatment against P. aeruginosa related diseases. Afzelin also promotes apoptosis to inhibit cell proliferation in breast cancer. It exhibits anti-asthmatic effects in a mouse model.

iNOS inhibitor, NADPH oxidase inhibitor

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable