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由来生物
rabbit
品質水準
物質
colorless
クローン
8K9R4, monoclonal
フォーム
liquid
分子量
30 kDa
交差性
human
濃度
0.4 mg/mL
テクニック
western blot: 1:500 - 1:2000
色
colorless
アイソタイプ
IgG
免疫原配列
PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KLK3(354)
詳細
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 162-261 of human PSA/KLK3 (P07288).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
アプリケーション
WB
保管分類コード
10 - Combustible liquids
WGK
WGK 1
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