SAB5702607

Anti-ESRα Antibody, clone 4L8K5, Rabbit Monoclonal

• 別名: ESR1,ER,ESR,ESRA,ESTRR,Era,NR3A1,ER alpha
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 4L8K5, monoclonal
• 形状: liquid
• 分子量: 66 kDa
• 化学種の反応性: human, rat, rat
• 濃度: 1.33 mg/mL
• テクニック: immunofluorescence: 1:50 - 1:200; western blot: 1:1000 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: AVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY
• UniProtアクセッション番号: P03372
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ESR1(2099)

詳細

詳細

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Estrogen Receptor alpha (ESRα) (P03372).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB, IF/ICC

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1