おすすめの製品
リコンビナント
expressed in HEK 293 cells
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
RM303, monoclonal
recombinant monoclonal
形状
buffered aqueous glycerol solution
化学種の反応性
human
テクニック
immunohistochemistry: 1:500-1:1000
western blot: 1:250-1:500
アイソタイプ
IgG
NCBIアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... PDGFRB(5159)
詳細
The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
特異性
This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).
免疫原
A peptide corresponding to the C-terminus of human CD140b.
生物化学的/生理学的作用
PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.
Molecular Cancer, 5(1), 37-37 (2006)
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Oncotarget, 8(13), 22059-22075 (2017)
PDGFRB gain-of-function mutations in sporadic infantile myofibromatosis.
Human Molecular Genetics, 26(10), 1801-1810 (2017)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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