SAB4504099

Anti-phospho-PKC-pan (pThr⁴⁹⁷) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-PKCL, Anti-PRKCL, Anti-nPKC-eta
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 76 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: P05129; P05771; P17252; P24723; Q02156; Q04759; Q05513; Q05655
• UniProtアクセッション番号: P24723
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr497)
• 遺伝子情報: human ... PRKCA(5578) , PRKCB(5579) , PRKCD(5580) , PRKCE(5581) , PRKCG(5582) , PRKCH(5583) , PRKCQ(5588) , PRKCZ(5590)

詳細

詳細

Protein kinase C is a member of the cAMP-dependent, cGMP-dependent, and protein kinase C (AGC) superfamily of protein kinases. It has more than14 isoforms. A catalytic domain with an ATP binding site and a substrate-binding site is found in all PKC isoforms.

免疫原

The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497.

Immunogen Range: 623-672

アプリケーション

Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit has been used in western blot analysis (1:500).

生物化学的／生理学的作用

Protein kinase Cs (PKCs) are involved in the growth and function of the gastrointestinal tract and the immune response. PKCs regulates cyclins, cyclin-dependent kinases (cdks), cdk inhibitors, and cell division cycle 25 (cdc25) phosphatases.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable