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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 49 kDa
化学種の反応性
human, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TEAD2(8463)
関連するカテゴリー
詳細
TEA domain transcription factor 2 (TEAD2) belongs to the TEAD family. TEAD2 gene is located on human chromosome 19q13.3 Anti-TEAD2 antibody detects endogenous levels of total TEAD2 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human TEAD2.
Immunogen Range: 71-120
Immunogen Range: 71-120
アプリケーション
Anti-TEAD2 antibody produced in rabbit has been used in western blotting.
生物化学的／生理学的作用
TEA domain transcription factor 2 (TEAD2) plays a regulatory role in cell stemness. It modulates the expression of several genes. TEAD2 participates in the maintenance of cell survival. It is essential during neural development. TEAD2 might be a new therapeutic target and a predictive indicator of hepatocellular carcinoma (HCC).
特徴および利点
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物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.
P Jacquemin et al.
Genomics, 55(1), 127-129 (1999-01-16)
Jong Seok Joo et al.
Oncology reports, 43(6), 1785-1796 (2020-04-24)
TEA Domain Transcription Factors (TEADs) are important in development and serve essential roles in tumorigenesis; however, the role of TEAD2 expression in hepatocellular carcinoma (HCC) has not been widely examined. The present study was conducted to investigate the expression status
Kotaro J Kaneko et al.
Genesis (New York, N.Y. : 2000), 45(9), 577-587 (2007-09-18)
TEAD2, one of the first transcription factors expressed at the beginning of mammalian development, appears to be required during neural development. For example, Tead2 expression is greatest in the dorsal neural crest where it appears to regulate expression of Pax3
Paula González-Alonso et al.
Cancers, 12(5) (2020-05-06)
Trastuzumab is the first-line targeted therapeutic drug for HER2-positive breast cancer, leading to improved overall survival. However, acquired resistance inevitably occurs. We aimed to identify, quantify, and assess the mechanisms of acquired resistance to trastuzumab. We established an acquired trastuzumab-resistant
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