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Merck
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Key Documents

SAB4502354

Sigma-Aldrich

Anti-PKC α antibody produced in rabbit

affinity isolated antibody

別名:

KPCA, PKC III, PKC-α, PKC-A, kinase PKC-α

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

antigen 76 kDa

化学種の反応性

human, mouse, rat

濃度

~1 mg/mL

テクニック

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... PRKCA(5578)

詳細

Anti-PKC α Antibody detects endogenous levels of total PKC α protein.
PKC α (protein kinase C α) gene is mapped to 17q24.2. PKC α is expressed in heart, liver, brain and epithelium.

免疫原

The antiserum was produced against synthesized peptide derived from human PKC alpha.

Immunogen Range: 606-655

生物化学的/生理学的作用

PKC (protein kinase C) is known to mediate different cellular processes, such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. While PKC is also associated with the learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC α (protein kinase C α) being one of the isozymes of the PKC family, it catalyzes the phosphorylation of substrates with many peptides.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase C?.
Lee S
The Journal of Biological Chemistry, 292(39), 16300-16309 (2017)
Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus
Panayiotis K. Yiallouros
Italian Journal of Pediatrics, 42: 67, 1-9 (2016)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)
Md Sajid Ghufran et al.
Cell biology and toxicology, 35(1), 67-80 (2018-07-08)
Aflatoxins are fungal metabolites classified into four major groups such as B1, B2, G1, and G2. These natural aflatoxins are designated as group I carcinogen by the International Agency for Research on Cancer. Among these, the aflatoxin B1 is more

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