SAB4501849

Anti-MDM2 antibody produced in rabbit

affinity isolated antibody

• 別名: Double minute 2 protein, HDM2, Oncoprotein Mdm2, Ubiquitin-protein ligase E3 Mdm2, p53-binding protein Mdm2
• MDL番号: MFCD00282354
• UNSPSCコード: 12352203
• NACRES: NA.41
• クローン: polyclonal
• application: ELISA; IF; WB
• 化学種の反応性: human, mouse
• テクニック: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• citations: 6

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 55 kDa
• 化学種の反応性: human, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBIアクセッション番号: Q00987
• UniProtアクセッション番号: Q00987
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MDM2(4193)

詳細

詳細

Anti-MDM2 antibody detects endogenous levels of total MDM2 protein.

Murine double minute 2 (MDM2) is an oncogenic protein. It is an E3 ubiquitin-protein ligase, that is mapped to human chromosome 12q15.

免疫原

The antiserum was produced against synthesized peptide derived from human MDM2.

Immunogen Range: 132-181

アプリケーション

Anti-MDM2 antibody has been used in immunohistochemistry.

生物化学的／生理学的作用

Murine double minute 2 (MDM2) is a negative regulator of the p53 tumor suppressor. It regulates cell cycle, cellular differentiation, cell fate determination, DNA repair and transcription. Epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells are induced by MDM2.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable