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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 61 kDa
化学種の反応性
human, rat, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... HSPD1(3329)
詳細
Anti-HSP60 antibody detects endogenous levels of total HSP60 protein.
Hsp60 (heat shock protein family D member 1) is a mitochondrial chaperone, located in the endoplasmic reticulum (ER). It is mapped to human chromosome 2q33.1.
免疫原
The antiserum was produced against synthesized peptide derived from human HSP60.
Immunogen Range: 511-560
Immunogen Range: 511-560
アプリケーション
Anti-HSP60, C-Terminal antibody has been used in SDS/PAGE and western blot analysis.
生物化学的/生理学的作用
Hsp60 (heat shock protein family D member 1) helps to gather proteins that are imported into mitochondrial matrix. Overexpression of Hsp60 results in Behcet′s Disease (BD),Crohn′s disease, juvenile dermatomyositis (JDM), and juvenile idiopathic arthritis (JIA) and rheumatoid arthritis (RA).
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
この製品を見ている人はこちらもチェック
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation
Febs Letters, 590(19), 3309-3322 (2016)
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
Nature, 337(6208), 620-625 (1989)
HSPD1 (heat shock 60kDa protein 1)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2007)
HSP60: a double edge sword in autoimmunity
Oncotarget, 6(32), 32299-32300 (2015)
Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis
Scientific Reports (2015)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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