SAB4500487

Anti-PARP (Cleaved-Asp²¹⁴) antibody produced in rabbit

affinity isolated antibody

• 別名: PARP
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 24 kDa
• 化学種の反応性: mouse, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; western blot: 1:500-1:1000
• NCBIアクセッション番号: P09874
• UniProtアクセッション番号: P09874
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: proteolytically cleaved (Asp214)
• 遺伝子情報: human ... PARP1(142)

詳細

詳細

Anti-PARP (Cleaved-Asp²¹⁴) Antibody detects endogenous levels of fragment of activated PARP (Cleaved-Asp²¹⁴) protein.

PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear protein that consists of three functional domains. It belongs to the PARP family. It is located on chromosome 1q42.

免疫原

The antiserum was produced against synthesized peptide derived from human PARP.

Immunogen Range: 165-214

アプリケーション

Anti-PARP (Cleaved-Asp214) antibody has been used in Western Blotting.

生物化学的／生理学的作用

PARP1 (poly (ADP-ribose) polymerase 1) participates in DNA repair. It serves as a facilitator of homologous recombination. It controls transcription by regulating chromatin structure, altering DNA methylation patterns, acting as a co-regulator of transcription factors and interacting with chromatin insulators. It also plays an important role in the protection of cardiovascular system.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable