SAB4200721

Anti-GABA antibody, Mouse monoclonal

clone GB-69, purified from hybridoma cell culture

• 別名: Mouse Anti-Gamma-aminobutyric acid
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: GB-69, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: rat, monkey, frog, mouse, human, gerbil
• 濃度: ~1.0 mg/mL
• テクニック: ELISA: suitable; dot blot: suitable; immunofluorescence: 5-10 μg/mL using human pancreatic tumor AsPC1 cell line; immunohistochemistry: 1-2.5 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human brain and/or cerebellum sections
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GABRA1(2554) ; mouse ... Gabra1(14394) ; rat ... Gabra1(29705) ; rhesus monkey ... Gabra1(574302)

詳細

詳細

Anti-GABA antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GB-69 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified GABA conjugated to BSA. γ-Aminobutyric acid (GABA) is present in the central nervous system (CNS) of vertebrates. GABA is formed following enzymatic decarboxylation of L-glutamic acid by glutamic acid decarboxylase (GAD).

免疫原

purified GABA conjugated to BSA

アプリケーション

Anti-GABA antibody, Mouse monoclonal has been used in:

• immunofluorescence
• immunohistochemistry
• enzyme linked immunosorbent assay (ELISA)
• dot-blot

生物化学的／生理学的作用

γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter. GABA mediates fast synaptic inhibition in the mature nervous system and plays multiple key roles as sensory circuits undergo functional development. GABA promotes proliferation of immune cells, embryonic stem cells and cortical progenitor cells. In addition, it is involved in protein synthesis and metabolism and plays a major role in the regulation of muscle tone, blood pressure, heart rate and respiration.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable