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Merck

SAB4200216

Sigma-Aldrich

Monoclonal Anti-Caveolin-1 antibody produced in mouse

enhanced validation

clone CAV1, tissue culture supernatant

別名:

抗CAV1抗体, 抗MSTP085抗体, 抗VIP21抗体

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse

結合体

unconjugated

抗体製品の状態

tissue culture supernatant

抗体製品タイプ

primary antibodies

クローン

CAV1, monoclonal

フォーム

buffered aqueous solution

分子量

antigen 22 kDa

化学種の反応性

rat, human, mouse

強化検証

independent
Learn more about Antibody Enhanced Validation

テクニック

immunohistochemistry: suitable
indirect immunofluorescence: 1:1000-1:2000 using human HUVEC or mouse 3T3 cells.
western blot: suitable

アイソタイプ

IgM

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... CAV1(857)
mouse ... Cav1(12389)
rat ... Cav1(25404)

詳細

Caveolin-1 (CAV1) is a multifunctional scaffolding protein, that has three exons. It is located on human chromosome 7q31.

免疫原

synthetic peptide corresponding to a sequence at the N-terminal of human caveolin-1, conjugated to KLH.

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Monoclonal Anti-Caveolin-1 antibody has been used in western blot analysis.

生物化学的/生理学的作用

Caveolin-1 may play a major role in the growth and evolution of cancer. It participates in glucose metabolism. It may also participate in angiogenesis. Cav-1 helps to control the expression of glucose transporters.

物理的形状

Culture supernatant solution containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

SAB4200216-BULK:
SAB4200216-VAR:
SAB4200216-25UL:
SAB4200216-200UL:


最新バージョンのいずれかを選択してください:

試験成績書(COA)

Lot/Batch Number

適切なバージョンが見つかりませんか。

特定のバージョンが必要な場合は、ロット番号またはバッチ番号で特定の証明書を検索できます。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Ye Xiong et al.
Oncotarget, 8(15), 24902-24914 (2017-02-18)
As the most prevalent primary brain tumor, gliomas are highly metastatic, invasive and are characteristic of high levels of glial cell-line derived neurotrophic factor (GDNF). GDNF is an important factor for invasive glioma cell growth; however, the underlying mechanism involved
Expression of flotilin-2 and acrosome biogenesis are regulated by MiR-124 during spermatogenesis
Wu Y, et al.
PLoS ONE, 10(8), e0136671-e0136671 (2015)
Margaret E Tome et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 38(12), 2209-2222 (2018-10-23)
P-glycoprotein (PgP) is the major drug efflux pump in human cerebral microvessels. PgP prevents pathogens, toxins and therapeutic drugs from entering the CNS. Understanding the molecular regulation of PgP activity will suggest novel mechanisms to improve CNS drug delivery. Previously
Adam C Midgley et al.
The Journal of biological chemistry, 290(18), 11218-11234 (2015-02-27)
Hyaluronan (HA) promotes transforming growth factor (TGF)-β1-driven myofibroblast phenotype. However, HA can also have disease-limiting activity. Bone morphogenetic protein-7 (BMP7) is an antifibrotic cytokine that antagonizes TGF-β1, and isolated studies have demonstrated that HA can both mediate and modulate BMP7
Joshua Chuck Harrell et al.
Cancer research, 67(21), 10582-10591 (2007-11-03)
The lymphatic system is a common avenue for the spread of breast cancer cells and dissemination through it occurs at least as frequently as hematogenous metastasis. Approximately 75% of primary breast cancers are estrogen receptor (ER) positive and the majority

資料

Quantitative and qualitative western blotting to validate knockdown by esiRNA. Sigma-Aldrich.com

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