SAB3701279

Anti-Human IgG (Fc specific), highly cross adsorbed-Biotin antibody produced in goat

affinity isolated antibody, lyophilized powder

• 別名: Goat Anti-Human IgG
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: goat
• 品質水準: 100
• 結合体: biotin conjugate
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: secondary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: human
• テクニック: ELISA: suitable; immunohistochemistry: suitable; western blot: suitable
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Immunoglobulin G (IgG) belongs to the immunoglobulin family. It is widely expressed and consists of a gamma heavy chain in the constant (C) region. IgG is a monomer with a molecular weight of about 150 kDa. The structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50 kDa and 25 kDa respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The Fc fragment contains the CH2 and CH3 domains of the antibody molecule. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.

特異性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Human IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Goat Serum, Human IgG, Human IgG F(c) and Human Serum. No reaction was observed against Human IgG F(ab′)2or Mouse serum proteins.

免疫原

Human IgG F(c) fragment

アプリケーション

Anti-Human IgG (Fc specific)-Biotin antibody produced in goat (highly cross adsorbed) has been used in immunohistochemistry and for binding detection in ligand binding assay.

物性

抗体フォーマット：IgG

物理的形状

0.02 M リン酸カリウム、0.15 M 塩化ナトリウム、pH 7.2、10 mg/mL ウシ血清アルブミン（BSA）-免疫グロブリン含有（プロテアーゼフリー）

再構成

Reconstitute with 1.0 mL deionized water (or equivalent).

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302,H311,H411
• 注意書き: P280 - P301 + P312 + P330 - P302 + P352 + P312
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2
• 補足的ハザード: EUH032
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable