SAB3701059

Anti-Mouse IgG IgA IgM (H+L), F(ab′)₂ fragment, highly cross adsorbed-Alkaline Phosphatase antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 別名: ALP, Alk Phos
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: goat
• 結合体: alkaline phosphatase conjugate
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: secondary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: mouse
• 濃度: 1.0 mg/mL
• テクニック: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Immunoglobulins (Igs) or antibodies are Y-shaped molecules which are the secreted form of the B-cell receptor. Igs are composed of two heavy and two light chains. An immunoglobulin possesses variable (V) domains that bind to antigens and constant (C) domains that bind to effector molecules. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. Pepsin cleaves the carboxy-terminal side of the disulfide bonds in the general region of the antibody and this gives rise to the F(ab′)2 fragment. The two antigen-binding arms of the antibody are linked in this fragment. There are five classes of immunoglobulins- IgM, IgA, IgG, IgD and IgE, classified based on their C regions.

特異性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities, pepsin digestion and chromatographic separation. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Alkaline Phosphatase and Anti-Goat Serum. No reaction was observed against Anti-Pepsin, Anti-Goat IgG F(c) or Human Serum Proteins. This reagent is suitable for the detection of all Mouse immunoglobulin subclasses and chain combinations.

免疫原

Mouse IgG IgA and IgM whole molecule

物性

抗体フォーマット：IgG F(ab')2

物理的形状

0.05 M トリスクロライド、0.15M 塩化ナトリウム、0.001M 塩化マグネシウム、0.0001M 塩化亜鉛、50％（v/v）グリセロール、pH 8.0、10 mg/mL ウシ血清アルブミン（BSA）-免疫グロブリン含有（プロテアーゼフリー）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable