SAB2101415

抗MAFB抗体 ウサギ宿主抗体

affinity isolated antibody

• 別名: 抗KRML抗体, 抗MGC43127抗体
• MDL番号: MFCD07370390
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 36 kDa
• 化学種の反応性: human, rat, guinea pig, horse, bovine, mouse, dog
• 濃度: 0.5 mg - 1 mg/mL
• テクニック: western blot: suitable
• UniProtアクセッション番号: Q9Y5Q3
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MAFB(9935)

詳細

詳細

MAF bZIP transcription factor B (MAFB) is encoded by the gene mapped to human chromosome 20q12. The encoded protein is a member of the maf oncogene family and is ubiquitously expressed in variety of tissues. MAFB is a 311 amino acid protein characterized with a typical basic leucine zipper (bZIP) domain in its C-terminal region.

免疫原

Synthetic peptide directed towards the N terminal region of human MAFB

生物化学的／生理学的作用

MAF bZIP transcription factor B (MAFB) has been implicated in the development of the hindbrain structures, thymus, interneurons, pancreatic islet cells and the hematopoietic system. In mouse, it helps in lip and palate development. MAFB regulates lineage-specific gene expression by suppressing the Ets-1-mediated transcription. The encoded protein plays an essential role in islet α-cell function. In addition, MAFB also regulates genes involved in both endocrine α- and β-cell differentiation. The protein acts as a modulator and marker of adipose tissue inflammation. Mutations in the gene is associated with the development of multicentric carpo-tarsal osteolysis (MCTO).

シーケンス

Synthetic peptide located within the following region: APQGSATAAEPQPGDPARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPE

物理的形状

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable