SAB1412229

ANTI-MAPK9 antibody produced in mouse

clone 3C12, purified immunoglobulin, buffered aqueous solution

• 別名: JNK-55, JNK2A, MAPK9
• UNSPSCコード: 12352203
• NACRES: NA.41
• クローン: 3C12, monoclonal
• application: ELISA (i); IF; WB
• 化学種の反応性: human
• テクニック: indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL
• citations: 1

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 3C12, monoclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 37.07 kDa
• 化学種の反応性: human
• テクニック: indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL
• アイソタイプ: IgG2aκ
• NCBIアクセッション番号: BC032539
• UniProtアクセッション番号: P45984
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MAPK9(5601)

詳細

詳細

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene′s mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

免疫原

MAPK9 (AAH32539, 321 a.a. ~ 424 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
ITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR

物理的形状

無色透明のPBS溶液、pH 7.4

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable