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Merck

SAB1305567

Sigma-Aldrich

Anti-β-Actin (ACTB) Antibody

mouse monoclonal, 8H10D10

別名:

ACTB

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

製品名

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse, clone 8H10D10, crude ascites, buffered aqueous solution

由来生物

mouse

抗体製品の状態

crude ascites

抗体製品タイプ

primary antibodies

クローン

8H10D10, monoclonal

フォーム

buffered aqueous solution

分子量

41737 Da

交差性

human

テクニック

immunohistochemistry: 1:10-1:50
western blot: 1:5000-1:20000

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... ACTB(60)

詳細

ACTB (actin β) gene codes for β-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. This gene is located on human chromosome 7p22.1.

アプリケーション

MONOCLONAL ANTI-BETA-ACTIN antibody has been used in western blotting.

生物化学的/生理学的作用

β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.

物理的形状

PBS(0.09% (W/V)アジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Mutschelknaus L, et al.
Scientific Reports, 7(1), 12423-12423 (2017)
Gabriela M Wright et al.
PloS one, 16(6), e0252927-e0252927 (2021-06-18)
Theoretically, small molecule CDK4/6 inhibitors (CDK4/6is) represent a logical therapeutic option in non-small cell lung cancers since most of these malignancies have wildtype RB, the key target of CDKs and master regulator of the cell cycle. Unfortunately, CDK4/6is are found
Lisa Mutschelknaus et al.
Scientific reports, 7(1), 12423-12423 (2017-10-01)
Radiation is a highly efficient therapy in squamous head and neck carcinoma (HNSCC) treatment. However, local recurrence and metastasis are common complications. Recent evidence shows that cancer-cell-derived exosomes modify tumour cell movement and metastasis. In this study, we link radiation-induced
Xinjun Lin et al.
Experimental and therapeutic medicine, 16(1), 204-212 (2018-06-14)
The present study aimed to evaluate the impact of dendrobium mixture (DMix) on the gene and protein expression of insulin signaling pathway-associated factors in the livers of diabetic rats. The molecular mechanisms by which DMix inhibits gluconeogenesis were also investigated.
Mengmeng Fan et al.
Oncology reports, 47(1) (2021-11-06)
The epithelial‑stromal interaction 1 gene (EPSTI1) is known to play multiple roles in the malignant progression of breast cancer and also in some aspects of the immune responses to the tumor. However, the relevance of the gene in the onset/progression

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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