S1701

抗SDCBP ウサギ宿主抗体

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: 抗MDA-9抗体, 抗ST1抗体, 抗SYCL抗体, 抗TACIP18抗体, 抗シンテニン抗体, 抗シンデカン結合タンパク質(シンテニン)抗体, 抗スキャフォールドタンパク質Pbp1抗体, 抗プロTGF-α細胞質ドメイン相互作用タンパク質18抗体, 抗黒色腫分化関連タンパク質-9抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• 形状: buffered aqueous solution
• 分子量: antigen ~30 kDa
• 化学種の反応性: mouse, human, rat
• 濃度: ~1.0 mg/mL
• テクニック: immunoprecipitation (IP): 10-20 μg using lysates of human HeLa cells; indirect immunofluorescence: 2-5 μg/mL using human HeLa cells; western blot: 2-4 μg/mL using whole extract of human HEK-293T cells, rat NRK cells, or mouse Neuro-2a cells
• UniProtアクセッション番号: O00560
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SDCBP(6386)

詳細

詳細

Syndecan binding protein (SDCBP), also known as syntenin and melanoma differentiation associated gene-9 (mda-9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. SDCBP contains tandemly repeated PDZ domains that binds the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. SDCBP is primarily localized to membrane associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.

アプリケーション

Anti-SDCBP antibody produced in rabbit has been used in:

• enzyme linked immuno sorbent assay (ELISA)
• immunoblotting
• immunocytochemistry

生物化学的／生理学的作用

Syndecan binding protein (SDCBP) regulates cytoskeletal-membrane organization, cell adhesion, protein trafficking and the activation of transcription factors. SDCBP promotes metastasis in human melanoma cells by activating c-Src.

物理的形状

0.01M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable