RAB0364

Human MMP-13 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• UNSPSCコード: 41116158
• NACRES: NA.32

特性

• 交差性: human
• 包装: kit of 96 wells (12 strips x 8 wells)
• テクニック: ELISA: suitable; capture ELISA: suitable
• 入力: sample type cell culture supernatant(s); sample type urine; sample type plasma; sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 6 pg/mL; standard curve range: 8.23-6000 pg/mL
• 検出方法: colorimetric
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... MMP13(4322)

詳細

詳細

The Human MMP-13 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-13 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human MMP13

アプリケーション

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

生物化学的／生理学的作用

MMP13 (matrix metalloproteinase 13) functions against different types of ECM (extracellular matrix) components. It gets activated by and activates multiple MMPs and hence, has a central role in the MMP cascade. This protein is frequently expressed in colorectal cancer (CRC) and this expression is linked with poor survival in CRC. MMP13 expression is absent in normal breast tissue, but is present in breast carcinoma suggesting its role in tumorigenesis. The expression of this protein can serve as a marker for tumor invasiveness, as its expression is induced during metastasis of multiple types of cancers, including squamous cell carcinomas of the head and neck and this expression is usually linked to poor prognosis. Missense mutation in this gene results in the autosomal dominant disorder called Missouri type of human spondyloepimetaphyseal dysplasia (SEMDMO), which is characterized by abnormal growth and modeling of vertebrae and long bones.

その他情報

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

キットの構成要素は別途購入可能です。

• RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Warning
• 危険有害性情報: H290
• 注意書き: P234 - P390
• 危険有害性の分類: Met. Corr. 1
• 保管分類コード: 8B - Non-combustible corrosive hazardous materials
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable