PLA0069

Rabbit anti-RPA70 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• 別名: 70kDa, HSSB, MST075, MSTP075, REPA1, RF-A, RF-A protein 1, RP-A, RP-A p70, RPA70, replication factor A protein 1, replication protein A1, replication protein A1 (70kD), single-stranded DNA-binding protein
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• グレード: Powered by Bethyl Laboratories, Inc.
• 化学種の反応性: human, mouse
• テクニック: immunohistochemistry: 1:1,000-1:5,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000-1:10,000
• アクセッション番号: NP_002936.1
• 輸送温度: wet ice
• 保管温度: 2-8°C
• 遺伝子情報: rabbit ... RPA70(6117)

詳細

免疫原

The epitope recognized by PLA0069 maps to a region between residues 350 and 400 of human replication protein A1, 70kDa using the numbering given in entry NP_002936.1 (GeneID 6117).

物理的形状

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

その他情報

Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable