P4623

Anti-phospho-Interferon-α Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-phospho-IFNα Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1, Anti-phospho-IFNARI
• MDL番号: MFCD07370443
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: rat, mouse, bovine, human
• テクニック: western blot: 1:1,000 using using FLAG^® immunoprecipitates from HEK 293 cells transfected with Mock, IFNAR1 wild type, or IFNAR1 S535A and S539A mutants
• UniProtアクセッション番号: P17181
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer535/pSer539)
• 遺伝子情報: human ... IFNAR1(3454) ; mouse ... Ifnar1(15975) ; rat ... Ifnar1(288264)

詳細

免疫原

synthetic phosphopeptide corresponding to the amino acid residues surrounding the human phospho-interferon-α receptor type I (pSer⁵³⁵/pSer⁵³⁹) subunit 1.

生物化学的／生理学的作用

Type I interferons (IFNα, IFNβ and IFNω) are pleotropic cytokines that mediate their cellular activities by binding to specific Type I IFN receptors. The functions of IFNα/ IFNα Receptor Type I axis include antiproliferative, antiviral and immunomodulatory activities.

物理的形状

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

法的情報

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)