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Merck

P4497

Sigma-Aldrich

Anti-Potassium Channel Kv1.3 (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

別名:

Anti-Voltage-gated Potassium Channel KV1.3

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

lyophilized powder

化学種の反応性

human, rat

テクニック

flow cytometry: 0.5-5 μg
western blot: 1:200-1:500 using rat brain membranes and human Jurkat T lymphocytes.

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

関連するカテゴリー

免疫原

synthetic peptide corresponding to amino acid residues 211-224 of human KV1.3. The sequence has 12/14 residues identical in rat and mouse.

物理的形状

Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

11 - Combustible Solids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Andreas Schulte-Mecklenbeck et al.
European journal of immunology, 45(9), 2602-2614 (2015-07-04)
Natural killer (NK) cells are a subset of cytotoxic lymphocytes that recognize and kill tumor- and virus-infected cells without prior stimulation. Killing of target cells is a multistep process including adhesion to target cells, formation of an immunological synapse, and
Joseph Andronic et al.
Biochimica et biophysica acta, 1828(2), 699-707 (2012-10-09)
Many functions of T lymphocytes are closely related to cell volume homeostasis and regulation, which utilize a complex network of membrane channels for anions and cations. Among the various potassium channels, the voltage-gated K(V)1.3 is well known to contribute greatly
T E DeCoursey et al.
Nature, 307(5950), 465-468 (1984-02-02)
Membrane receptors and ion transport mechanisms probably have an important role in lymphocyte activation leading to T-lymphocyte proliferation in the immune response. Here we have applied a gigaohm-seal patch clamp technique to reveal the identity and properties of ion channels
R S Lewis et al.
Annual review of immunology, 13, 623-653 (1995-01-01)
Over the past decade, a variety of ion channels have been identified and characterized in lymphocytes by use of the patch-clamp technique. This review discusses biophysical and regulatory aspects of lymphocyte potassium and calcium channels with the aim of understanding
Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

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