P1306

Peptide YY human

≥97% (HPLC), synthetic

• 別名: PYY
• 実験式（ヒル表記法）: C₁₉₄H₂₉₅N₅₅O₅₇
• CAS番号: 118997-30-1
• 分子量: 4309.75
• MDL番号: MFCD00081843
• UNSPSCコード: 51111800
• NACRES: NA.32

特性

• 由来生物: synthetic
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• フォーム: solid
• UniProtアクセッション番号: P10082
• 保管温度: −20°C
• 遺伝子情報: human ... PYY(5697)

詳細

Amino Acid Sequence

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2

詳細

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

アプリケーション

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

生物化学的／生理学的作用

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

その他情報

Lyophilized from 0.1% TFA in H2O

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)