N8159

アルブミン, ニトロ化 ウシ血清由来

lyophilized powder

• 別名: ニトロ化BSA
• CAS番号: 9048-46-8
• MDL番号: MFCD03454307
• UNSPSCコード: 12352202
• NACRES: NA.41

特性

• 由来生物: bovine
• 品質水準: 200
• 形状: lyophilized powder
• テクニック: immunoblotting: suitable
• UniProtアクセッション番号: P02769
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: bovine ... ALB(280717)

詳細

詳細

Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.

アプリケーション

Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).

生物化学的／生理学的作用

Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.

物理的形状

凍結乾燥品(0.01M PBS溶液, pH 7.4)

調製ノート

ペルオキシ亜硝酸でニトロ化したウシ血清アルブミン(BSA)です。

アナリシスノート

アジ化ナトリウムを含有しません。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable