N7785

β-ニコチンアミドアデニンジヌクレオチド 2′-リン酸(還元型) 四ナトリウム塩

vial of 10 mg, ~95%

• 別名: β-NADPH, 2′-NADPH, NADPH Na₄, TPNH₂ Na₄, コエンザイム II(還元型) 四ナトリウム塩, ジヒドロニコチンアミドアデニンジヌクレオチドリン酸 四ナトリウム塩, トリホスホピリジンヌクレオチド(還元型) 四ナトリウム塩
• 実験式（ヒル表記法）: C₂₁H₂₆N₇Na₄O₁₇P₃
• 分子量: 833.35
• EC Number: 214-664-6
• MDL番号: MFCD00036263
• UNSPSCコード: 41106305
• PubChem Substance ID: 24897841
• NACRES: NA.51

特性

• アッセイ: ~95%
• 品質水準: 200
• 形状: powder
• 包装: vial of 10 mg
• InChI: 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
• InChI Key: WYWWVJHQDVCHKF-MPUNMZHWSA-J

詳細

アプリケーション

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay.

生物化学的／生理学的作用

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP⁺) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP⁺:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP⁺/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).

調製ノート

還元型

その他情報

容量は、UV-可視吸光法で定量したNADPH含量に基づいています。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)