N3893

抗一酸化窒素合成酵素, 内皮 (1185-1205) ウサギ宿主抗体

IgG fraction of antiserum, buffered aqueous solution

• 別名: 抗eNOS抗体
• MDL番号: MFCD01092428
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 135 kDa
• 化学種の反応性: bovine, mouse, rat, human
• テクニック: immunohistochemistry (frozen sections): 1:100 using acetone-fixed, frozen tissue sections of mouse heart; microarray: suitable; western blot: 1:10,000 using bovine lung endothelial cell extract
• UniProtアクセッション番号: P29474
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NOS3(4846) ; mouse ... Nos3(18127) ; rat ... Nos3(24600)

詳細

詳細

Endothelial nitric oxide synthase (eNOS) is a 135 kDa protein and is an isoform of NOS. eNOS expression is not limited to the endothelium of blood vessels, it is also expressed in the epithelium of several tissues, including the bronchial tree. It is also localized in neurons in the brain, especially the pyramidal cells of the hippocampus.

The gene encoding endothelial nitric oxide synthase (eNOS) is localized on chromosome 7q35-36 and has 26 exons.

免疫原

ウシ内皮由来NOシンタ-ゼ(eNOS)のアミノ酸1185-1205に相当する合成ペプチド(N末端リジン付加)のKLH結合体。免疫原の配列は、ヒトeNOSで高度に保存されています。

アプリケーション

Anti-Nitric Oxide Synthase, Endothelial (1185-1205) antibody produced in rabbit has been used in immunoblotting and immunohistochemistry.

生物化学的／生理学的作用

Endothelial nitric oxide synthase (eNOS) has been studied as a modulator of vascular function and it is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.

物理的形状

0.01M PBS溶液 (pH 7.4, 15mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable