M9441

肝臓由来ミクロソーム, プール品

from mouse(CD-1), male

• 別名: lab equipment accessory
• UNSPSCコード: 12161501
• NACRES: NA.47

特性

• 由来生物: mouse (CD-1)
• 品質水準: 200
• フォーム: liquid
• 包装: vial of ~10 mg
• UniProtアクセッション番号: Q91VS7
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: mouse ... Mgst1(56615)

詳細

詳細

Microsomes are the fraction of "submicroscopic” particles isolated from homogenates of liver and other tissues. Microsomes are rich in ribonucleic acid (RNA).

アプリケーション

Microsomes from Liver, Pooled has been also been used to study the metabolic stability of antitumor agents and tunicamycin.

Microsomes from Liver, Pooled has been used in cell survival and mutation assays in Escherichia coli.

生物化学的／生理学的作用

肝ミクロソ-ムは、肝細胞の小胞体由来の細胞内粒子です。これらのミクロソ-ムには、シトクロムP-450など多くの薬剤代謝酵素が含まれています。各生物種由来のミクロソ-ムプ-ル品は、異物代謝および薬剤相互作用の研究にご利用いただけます。

Microsomes might act as cell organelles and are actively involved in protein synthesis. Carbon monoxide-binding pigment of microsomes, named P-450, is an integral element of mixed function oxidase systems involved in the oxidative demethylation and hydroxylation of drugs and steroids. Murine liver microsomes plays a crucial role in degradation of small antimicrobial β^2,2-amino acid derivatives.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable