おすすめの製品
由来生物
Escherichia coli (O127:B8)
品質水準
フォーム
lyophilized powder
精製方法
gel-filtration chromatography
不純物
<1% Protein
色
white to yellow cast
溶解性
water: soluble
輸送温度
ambient
保管温度
2-8°C
類似した製品をお探しですか? 訪問 製品比較ガイド
詳細
This product is extracted from E. coli serotype O127:B8 and purified by gel filtration. The source strain is ATCC 12740. This LPS serotype has been used in the study of septic shock and to induce NOS in murine macrophages and PAF synthesis in rat glomerular masangial cells.
アプリケーション
リポポリサッカリド(LPS)は、グラム陰性菌細胞壁の特徴的な構成要素です。LPS及びそのリピドA部分は、一般的な病原体関連分子パターン(PAMP)を認識するToll様受容体タンパク質ファミリーのメンバーであるToll様受容体4(TLR4)により自然免疫系細胞を刺激します。
生物化学的/生理学的作用
Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.
調製ノート
The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.
その他情報
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
関連製品
製品番号
詳細
価格
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 2 Oral
保管分類コード
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
L3137-25MG-PW:
L3137-BULK:
L3137-VAR:
L3137-5MG-PW:
L3137-5MG:
L3137-10MG-PW:
L3137-25MG:
L3137-10MG:
この製品を見ている人はこちらもチェック
Taichiro Nonaka et al.
The Journal of clinical investigation, 126(4), 1367-1382 (2016-03-15)
Most skin cancers develop as the result of UV light-induced DNA damage; however, a substantial number of cases appear to occur independently of UV damage. A causal link between UV-independent skin cancers and chronic inflammation has been suspected, although the
Evelin Painsipp et al.
PloS one, 6(6), e20719-e20719 (2011-06-16)
Immune challenge by bacterial lipopolysaccharide (LPS) causes short-term behavioral changes indicative of depression. The present study sought to explore whether LPS is able to induce long-term changes in depression-related behavior and whether such an effect depends on mouse strain and
Choon Kit Tang et al.
Biomaterials, 30(7), 1389-1400 (2008-12-09)
Receptor mediated gene delivery is an attractive non-viral method for targeting genetic material to specific cell types. We have previously utilized oxidized (OMPLL) and reduced mannan poly-L-lysine (RMPLL) to target DNA vaccines to antigen presenting cells and demonstrated that it
Eugene S Yim et al.
Journal of biomedical materials research. Part A, 91(3), 894-902 (2008-12-17)
Hydrogel polymers comprise a novel category of synthetic materials being investigated for use in cartilage replacement. One candidate compound, a poly(ethylene glycol)/poly(acrylic acid) (PEG/PAA) interpenetrating polymer network (IPN), was developed for use in corneal prostheses and was recently engineered for
Mitsuaki Moriyama et al.
Neurochemical research, 41(11), 3138-3146 (2016-11-04)
The biomolecule acetate can be utilized for energy production, lipid synthesis, and several metabolic processes. Acetate supplementation reduces neuroglial activation in a model of neuroinflammation induced by intraventricular injection of lipopolysaccharide (LPS). To investigate the mechanisms underlying the anti-inflammatory effect
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら(テクニカルサービス)