L1045

LY-354740水和物

≥98% (HPLC)

• 別名: (1S,2S,5R,6S)-2-アミノビシクロ[3.1.0]ヘキサン-2,6-ジカルボン酸, LY-354740, エグルメガド
• 実験式（ヒル表記法）: C₈H₁₁NO₄ · xH₂O
• 分子量: 185.18 (anhydrous basis)
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: solid
• 溶解性: deionized water: 8 mg/mL
• オーガナイザー: Eli Lilly
• 保管温度: room temp

詳細

アプリケーション

LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum.

生物化学的／生理学的作用

LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice.

特徴および利点

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable