L0544

Monoclonal Anti-Leukemia Inhibitory Factor antibody produced in rat

clone 139124, purified immunoglobulin, lyophilized powder

• 別名: Anti-Lif
• UNSPSCコード: 51111800
• NACRES: NA.41
• クローン: 139124, monoclonal
• application: WB
• 化学種の反応性: mouse
• テクニック: western blot: 1-2 μg/mL
• citations: 3

特性

• 由来生物: rat
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 139124, monoclonal
• フォーム: lyophilized powder
• 化学種の反応性: mouse
• テクニック: western blot: 1-2 μg/mL
• アイソタイプ: IgG2b
• UniProtアクセッション番号: P09056
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Lif(16878)

詳細

免疫原

purified, E. coli-derived recombinant mouse leukemia inhibitory factor.

生物化学的／生理学的作用

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.

物理的形状

凍結乾燥品(PBS溶液, 5%トレハロース含有, 0.2 μmフィルター滅菌済み)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)