GERPN6302

Iodoacetamide

Cytiva RPN6302, pack of 25 g

• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• フォーム: solid
• 特徴: wetted part: no
• 包装: pack of 25 g
• メーカー／製品名: Cytiva RPN6302
• 色: Yellowish
• 溶解性: cold water: soluble (Easily soluble in cold and hot water)
• 保管温度: 2-8°C

詳細

詳細

Used for the efficient alkylation of thiols while minimizing oxidation of competing thiol pairs in protein samples.

アプリケーション

Iodoacetamide has been used:

• as a component in urea-sodium dodecyl sulfate (SDS) buffer for yeast cell lysis in immunoprecipitation assay
• in equilibration of pH gradient strips during the second dimension run in isoelectric focusing
• as a protein alkylation agent

生物化学的／生理学的作用

Iodoacetamide (IAA) modifies thiol groups in proteins by S-carboxyamidomethylation. Iodoacetamide is an alkylating agent. IAA is commonly used to analyze the key role of cysteine residues in the catalytic reactions of enzymes. It is also used in the derivatization of cysteine residues in proteins for proteomic analysis. IAA irreversibly inhibits glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

特徴および利点

• Ultrapure, proteomic-grade iodoacetamide is used for efficient alkylation of thiols while minimizing oxidation of the competing thiol pairs in protein samples.

保管および安定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

アナリシスノート

この製品の分析証明書は、www.cytiva.com.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H301,H334,H317,H413
• 注意書き: P280 - P273 - P261 - P342 + P311 - P301 + P310 - P405 - P501
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects