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ligand
(Multimodal strong anion exchanger)
メーカー/製品名
Cytiva 17371501
Matrix
high-flow agarose
平均部品サイズ
40 μm (median particle size of the cumulative volume distribution)
cleaning in place
2-14
動作範囲
3-12
キャパシティ
45-85 mg Mab/ml binding capacity (Chromatography Medium)
詳細
The multimodal anion exchanger ligand of Capto adhere ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions.
The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.
Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development.
As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.
The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.
Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development.
As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.
特徴および利点
Capto adhere ImpRes is a strong anion exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules.
- High yields achieved through the high-resolution beads and selectivity of the ligand.
- Efficient removal of aggregates, viruses, and main contaminants in MAb processes.
- Enables use of a platform approach to MAb process development.
- Allows separation of MAb charged variants.
保管および安定性
Store at 4 to 30 °C (20% ethanol)
アナリシスノート
この製品の分析証明書は、www.cytiva.com.
シグナルワード
Warning
危険有害性情報
保管分類コード
3 - Flammable liquids
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資料
In these studies, the binding capacity for MAbs and the efficiency in the clearance of impurities using Capto adhere ImpRes in bind/elute mode was evaluated.
This page describes the maintenance of media and storage conditions for multimodal chromatography using GE Healthcare products.
プロトコル
Capto adhere ImpRes is a cost-effective and flexible chromatography medium from GE Healthcare, designed for high-resolution polishing of MAbs.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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