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詳細
Ion Exchanger Type (value)
包装
pack of 5 × 1 mL
メーカー/製品名
Cytiva 11-0032-73
パラメーター
flow rate
<4 ml/min flow rate
42 psi
ベッドサイズ
7 mm × 25 mm
ベッド容積
1 mL
カラム内径
7 mm
Matrix
highly cross-linked agarose
平均部品サイズ
75 μm (d50v)
cleaning
2-14
動作範囲
2-12
適合性
suitable for bioprocess medium
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関連するカテゴリー
詳細
HiTrap® Capto™ MMC is prepacked with Capto™ MMC, a multimodal BioProcess ion exchange medium. The multimodal functionality gives a different selectivity compared with traditional ion exchangers and it binds proteins at high or low ionic strength.
アプリケーション
The multimodal functionality gives a different selectivity compared with traditional ion exchangers including binding of Proteins regardless of ionic strength of the loading material . This means that the medium may be used for direct load of clarified feedstocks, without prior dilution to reduce the conductivity of the starting material. To reduce tedious sample preparation, the top filter in HiTrap® Capto™ MMC has been optimized for loading sonicated unclarified cell lysate directly on the column.
The Capto™ MMC ligand may interact with Proteins in many different ways. It contains a carboxyl group, and thus it is a weak cation exchanger. However, in addition to the ionic interactions several other types of interactions are involved, including hydrogen bonding and hydrophobic interaction.
The Capto™ MMC ligand may interact with Proteins in many different ways. It contains a carboxyl group, and thus it is a weak cation exchanger. However, in addition to the ionic interactions several other types of interactions are involved, including hydrogen bonding and hydrophobic interaction.
特徴および利点
- High dynamic binding capacity at high conductivity.
- Selectivity allows binding in the presence of salt.
- High volume throughput.
- HiTrap® Capto™ MMC can be used to bind Proteins at the conductivity of the feed material and to solve specific purification challenges.
保管および安定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
アナリシスノート
この製品の分析証明書は、www.cytiva.com.
その他情報
1)The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.
法的情報
Capto is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
シグナルワード
Warning
危険有害性情報
保管分類コード
3 - Flammable liquids
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