G0549

Corosolic acid from Lagerstroemia speciosa

≥98% (HPLC)

• 別名: Corosolic acid, (2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid, 2α-Hydroxyursolic acid, Colosolic acid, Corsolic acid, Glucosol
• 実験式（ヒル表記法）: C₃₀H₄₈O₄
• CAS番号: 4547-24-4
• 分子量: 472.70
• MDL番号: MFCD06794973
• UNSPSCコード: 12352106
• PubChem Substance ID: 329799816
• NACRES: NA.25

特性

• 品質水準: 200
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 溶解性: methanol: 1 mg/mL, clear, colorless
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: 2-8°C
• SMILES記法: O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1
• InChI: 1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
• InChI Key: HFGSQOYIOKBQOW-ZSDYHTTISA-N

詳細

詳細

Corosolic acid from Lagerstroemia speciosa is a pentacyclic triterpenoid found in a variety of plants, such as apples, basil, bilberries, cranberries, and prunes. It is a natural derivative of ursolic acid.

アプリケーション

Corosolic acid from Lagerstroemia speciosa has been used to study the inhibiting activity of ursolic acid and its derivative against colon cancer cells by causing degradation of β-catenins.

生物化学的／生理学的作用

Corosolic acid from Lagerstroemia speciose shows a variety of biological activities such as anti-proliferation, apoptosis, and anti-carcinogenic. It exhibits an inhibiting effect on the post-challenge plasma glucose levels in humans. Corosolic acid, due to its ability to improve glucose metabolism, has been touted to be used in the management of Type-2 Diabetes. It improves hypertension, oxidative stress, and inflammation, thereby being a potential candidate to be used against atherosclerosis-related diseases.

Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable